Antibacterial Activity of Bandotan (Ageratum conyzoides L) Leaves Extracts Against Methicillin-Resistant Staphylococcus aureus
- Jurnal Nasional Terakreditasi
- Selvira Anandia Intan Maulidya, Doni Anshar Nuari, Shendi Suryana, dan Sumia Almarifah
- Borneo Journal of Pharmacy, Vol. 3 issue 4 November 2020, Hal 243-248, e-ISSN: 2621-4814, DOI: https://doi.org/10.33084/bjop.v3i4.1552
Abstrak
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial infections worldwide and can also be life-threatening. This study aims to determine the antibacterial activity of the ethanolic extract of Bandotan leaves (Ageratum conyzoides L) on the growth of MRSA. The leaves of Ageratum conyzoides were extracted with ethanol and filtered for their phytochemical content. The ethanol extract of A. conyzoides leaves was evaluated for its potential antibacterial activity using the disc diffusion test. Minimum inhibitory concentration (MIC) values were determined using the agar dilution method. Phytochemical screening showed that the extract contained alkaloids, flavonoids, saponins, tannins, and steroids or triterpenoids. Ageratum conyzoides leaf extract showed an inhibition zone of 25.1 mm at an extract concentration of 12.5% with MIC value
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